Cognitive Factors Preceding Alzheimer’s Disease Examined

Study identifies four cognitive factors likely seen up to three years prior to disease onset


THURSDAY, Oct. 15 (HealthDay News) — The onset of Alzheimer’s disease can be seen on tests for several cognitive factors up to three years prior to clinical diagnosis, according to a study in the October issue of the Archives of Neurology.

David K. Johnson, Ph.D., of the University of Kansas in Lawrence, and colleagues analyzed data on 444 seniors enrolled by the Alzheimer Disease Research Center between 1979 and 2006. To identify preclinical signs of Alzheimer’s disease, the researchers evaluated four cognitive factors including global, verbal memory, visuospatial, and working memory. The trends were compared for individuals who developed Alzheimer’s disease and those who did not.

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