Reuters: Fewer die after treatment at stroke centers

By Genevra Pittman

NEW YORK | Tue Jan 25, 2011 5:26pm EST

NEW YORK (Reuters Health) — People treated for stroke at designated stroke centers appear to survive slightly longer than those treated at other hospitals, suggests a new study.

While the finding has important implications, it doesn’t change the most important message about stroke, which is to get help as soon as possible, said study author Dr. Ying Xian of the Duke Clinical Research Institute in Durham, North Carolina, and formerly of the University of Rochester Medical Center in New York, where he did the research.

“The most important thing for the patient is when you have a stroke attack, or you see people stroke attack, call 911 immediately,” he told Reuters Health. “Ideally, the EMS will transport people to the appropriate hospital.”

Most strokes occur when a blocked blood vessel causes some of the blood flow going to the brain to be cut off, damaging brain tissue that depends on that blood to survive.

Stroke is the third leading cause of death in the U.S., only topped by heart disease and cancer. Each year, nearly 800,000 people in the U.S. have a stroke and more than 130,000 people die as a result.

Within the last decade, both national and state programs have begun designating hospitals as official stroke centers when they demonstrate certain staff, facilities, and services believed to improve a patient’s outcome.

In addition, states such as New York require ambulances to take stroke patients straight to a designated center, as long as they can get care within two hours.

In the new study, published in the Journal of the American Medical Association, Xian and his colleagues tracked every adult admitted between 2005 and 2006 to a New York State hospital after an ischemic stroke, the most common type. About half of the nearly 31,000 patients ended up at stroke centers, while the rest were treated at hospitals without the designation.

One month after their treatment, 10.1 percent of the patients treated at stroke centers had died, compared to 12.5 percent of patients treated at other hospitals. A year later, those numbers were 22.3 percent and 26 percent, respectively.

The researchers also found that patients going to stroke centers were more likely to be treated with drugs that dissolve blood clots, but need to be given within a few hours of a stroke.

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Social Isolation Makes Strokes More Deadly

COLUMBUS, Ohio — New research in mice suggests that social isolation may promote more damaging inflammation in the brain during a stroke.

Researchers at Ohio State University found that all the male mice that lived with a female partner survived seven days after a stroke, but only 40 percent of socially isolated animals lived that long. In addition, the paired mice suffered much less brain damage than did the surviving solitary mice.

“Under nearly every measure, it seems that there was something about living together that protected the mice by reducing the damaging inflammatory response,” said Kate Karelina, lead author of the study and a doctoral student in neuroscience at Ohio State University.

Overall, the study provides some early clues as to how social support may protect people who suffer strokes. “We’re learning more about what it is about social support that helps stroke victims have more positive outcomes,” Kate Karelina said. Click Here for the full article.